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But in FMA, it is shown that Ed dies, but actually what happens is that he is sent into our world along with his father. So, for Al, Winry and other characters he sacrificed himself to give Al his body back, but instead he is sent into our world.
According to here 2003 Edward has indirectly or directly killed at least four beings. Two were humans, Majhal and Mugear, while the other two were Homunculi, Greed and Sloth.
Edward loses his ability to perform alchemy after using his Gate Of Truth as the toll in order to bring Alphonse back, though he still retains his knowledge of alchemy, full of the truth of this background.
Edward sacrifices his ability to perform alchemy to fully restore Alphonse, while Lin receives a Philosopher’s Stone. Hohenheim goes to visit Trisha’s grave, where he dies peacefully. The Elrics return home, but separate two years later to research alchemy further.
The Flame Alchemist was arguably the third most important character in the series—after Edward and Alphonse Elric—but he was also the most powerful in terms of strength. Mustang’s gloves were embroidered with transmutation circles and created a spark whenever he rubbed his fingers together.
Although he defeated Father in first round of their battle, latter he was only defeated when Father revealed his amorphous undamagable shadow form and enveloped him.
Hohenheim
Van Hohenheim was exactly not immortal. He receive life forces by consuming the souls of his philosopher stone. And stone has a limit so when the stone completely wears out, he died. Everything has a limit, even philosopher stone.
Envy is actually Ed’s brother. He is one of the seven Homonculi in the series. Envy has the ability to shape shift into a variety of different characters in the series. Hohenheim, his (and Ed and Al’s) father, tried to bring Envy back from the dead after he died of mercury poisoning at a very young age.
Found still alive by travelers from the eastern nation of Xing, Hohenheim was brought there and regained his strength while coming to an understanding with each of the souls inside him and teaching Alchemical principles to the Xingese people.
In the first anime Winry continues traveling with the Elrics until she learns that her parents were killed in the Ishvalan massacre by Ed’s superior Roy Mustang on military orders. In the movie sequel, Winry learns of Izumi’s death.