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Microorganisms, most notably yeast and bacteria, are used in research and industry for cloning genes, replicating DNA and producing purified proteins. Yeast, in particular, is widely used as a model organism for studying a variety of cell functions.
Microbial biotechnology, enabled by genome studies, will lead to breakthroughs such as improved vaccines and better disease-diagnostic tools, improved microbial agents for biological control of plant and animal pests, modifications of plant and animal pathogens for reduced virulence, development of new industrial …
For example, each human body hosts 10 microorganisms for every human cell, and these microbes contribute to digestion, produce vitamin K, promote development of the immune system, and detoxify harmful chemicals. And, of course, microbes are essential to making many foods we enjoy, such as bread, cheese, and wine.
They are usually organisms that are easy to maintain and breed in a laboratory setting. For example, they may have particularly robust embryos? that are easily studied and manipulated in the lab, this is useful for scientists studying development.
Animal models are used to obtain information about a disease and its prevention, diagnosis, and treatment. By using animals, researchers can carry out experiments that would be impractical or ethically prohibited with humans.
When animal models are employed in the study of human disease, they are frequently selected because of their similarity to humans in terms of genetics, anatomy, and physiology. Also, animal models are often preferable for experimental disease research because of their unlimited supply and ease of manipulation.
The term “animal testing” refers to procedures performed on living animals for purposes of research into basic biology and diseases, assessing the effectiveness of new medicinal products, and testing the human health and/or environmental safety of consumer and industry products such as cosmetics, household cleaners.
When an animal’s genes change, or mutate, the new form of the animal that results is a mutant. You can use the scientific term mutant for any plant or animal that’s the result of a change, or mutation, in the DNA of that organism.
Types of Changes in DNA
Class of Mutation | Type of Mutation | Human Disease(s) Linked to This Mutation |
---|---|---|
Point mutation | Substitution | Sickle-cell anemia |
Insertion | One form of beta-thalassemia | |
Deletion | Cystic fibrosis | |
Chromosomal mutation | Inversion | Opitz-Kaveggia syndrome |
Scientists believe that every time the human genome duplicates itself there are around 100 new mutations. They’re pretty common, and usually negligible. However, it would stand to reason that within the pantheon of human mutations, some would express themselves in the form of extraordinary superhuman abilities.
1. Progeria. This genetic disorder is as rare as it is severe. The classic form of the disease, called Hutchinson-Gilford Progeria, causes accelerated aging.
In fact, the G-T mutation is the single most common mutation in human DNA. It occurs about once in every 10,000 to 100,000 base pairs — which doesn’t sound like a lot, until you consider that the human genome contains 3 billion base pairs.
There are three types of DNA Mutations: base substitutions, deletions and insertions.
Many mutations have no effect at all. These are called silent mutations. But the mutations we hear about most often are the ones that cause disease. Some well-known inherited genetic disorders include cystic fibrosis, sickle cell anemia, Tay-Sachs disease, phenylketonuria and color-blindness, among many others.